Endocrine Abstracts

Introduction: Hashimoto’s thyroiditis (HT) is common autoimmune thyroid disorder and is predominantly the clinical expression of cell-mediated immunity leading to destruction of thyroid cells. Vitamin D plays a role in the regulation of immunity and cell proliferation. So, do the serum levels of vitamin D reduced in HT?Methods: We examined the medical records of the ‘Thyroid policlinic’ patients with or without HT. Vitamin D, thyroid autoa...

Papillary thyroid carcinoma (PTC) is most frequent endocrine cancer on the other hand papillary microcarcinoma can be seen increasing frequency in recent years. In this study we compare clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma retrospectively.Eighty one PTC and 38 PMC total 119 patients followed between 2005 and 2009 were enrolled study. Average follow-up time is 35 months in PTC a...

Introduction: Thyroid lymphoma is a rare disease. Furthermore, coincidence of extrathyroidal lymphoma is very rare.Case: A 69 years-old woman patient was admitted to the hospital with dyspnea, hoarse voice and swelling of throat for a month. In her history, she had been diagnosed as gastric lymphoma 6 years ago, while she was being investigated for upper gastrointestinal bleeding. Six cures of chemotherapy has been applied. She was not on follow up. In p...

Introduction: Schwachman–Diamond syndrome (SDS) is usually manifested with exocrine pancreatic insufficiency, short stature, and chronic neutropenia. SDS associated with osteoporosis and diabetes mellitus (DM) presenting with ketoacidosis is quite rare.Case: A 29-year-old woman was admitted to emergency room with symptoms of frequent urination and confusion. She had not history of diabetes mellitus or any other disease. On her examination, she had n...

Objective: Acromegaly is associated with increased morbidity and mortality, mostly due to cardiovascular complications. The objective of the present study was to evaluate the echocardiographic epicardial fat thickness in acromegaly patients.Methods and results: We evaluated 25 consecutive patients with acromegaly (15 females, 10 males, mean age 44.5±10.1 years), and 22 age-matched control subjects (12 females, 10 males, mean age 37.40±7.5 years...

Introduction: The evidence shows that the prevalence of metabolic syndrome is increased in patients with hypogonadism. However, much of the data regarding this association comes from the elderly patients with obesity, hypertension or type 2 diabetes. The total testosterone levels alter physiologically in these conditions and thus can falsify the association. We aimed to investigate the prevalence of the metabolic syndrome in young adults with hypogonadism who do not have any c...

The high-density lipoprotein (HDL) levels are decreased in paitents with hypogonadotropic hypogonadism (HH). Although testosteron regulates lipoprotein metabolism, the effect of testosterone replacement therapy on HDL metabolism is not clearly shown in HH. The aim of this study is to determine the effects of testesterone replacement on HDL subfractions in young patients with HH. Forty-three cases with HH (mean age 21±2.45 years) were enrolled. Fifty-one healthy volunteer ...

Benign symmetric lipomatosis (BSL) is a very rare disorder characterized by the growth of uncapsulated masses of adipose tissue, predominantly located in the neck and shoulders. Benign symmetric lipomatosis is usually described in adults between 30 and 60 years of age and is slightly more frequent in men with heavy alcohol consumption. A 70-year-old woman presented with a great growth of soft tissues in the cervico-occipital region who had never consumed any alcohol. Laborator...

Diabetic ketoacidosis (DKA) seen in 10–70% of patients with type 1 diabetes mellitus (DM1) has a significant risk of mortality. We present a DKA in a patient with DM1 resulted in hypokalemia related ECG abnormalities that the diagnosis needed to be differentiated from acute coronary syndrome. A 18-year-old women without any significant past medical history admitted to hospital with a two day history of fatique, weakness, nausea, vomiting. Patient appeared hipovolemic. Vit...

Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. But histological findings support the thesis that ‘plantar fasciitis’ is a degenerative fasciosis without inflammation. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, we aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabete...